Newormics hosted this webinar introducing the high-throughput version of our system, the vivoChip-96x, and how it has been used for large-scale screens. Dr. Sudip Mondal of UT Austin, presents his work on high-throughput, high-content screens of chemical libraries in C. elegans, which were performed using the vivoChip-96x and integrated imaging system.
C. elegans is rapidly gaining interest as an animal alternative in vivo model for toxicology and drug candidate screening, but high-resolution imaging of the thousands of animals necessary for large phenotypic screens has been impossible with existing technology. Dr. Mondal will show how large-scale phenotypic screening was performed in the vivoChip-96x to identify compounds of interest.
Newormics presents a 30 minute live webinar on the applications of the vivoChip® for rapid immobilization of up to 40 C. elegans within minutes and high-resolution imaging in any microscope. During this webinar, we will demonstrate how the vivoChip can accelerate researchers’ workflow in the lab and enables high-throughput and high-content studies on the following topics: High-resolution imaging of C. elegans germline in three dimensions; C. elegans for assessing developmental and reproductive toxicity; C. elegans for assessing developmental neurotoxicity
This webinar would be useful for: researchers in the C. elegans community doing high-resolution imaging or phenotypic scoring of neurons, germline cells, or other tissues; assay developers performing chemical library or RNAi screens in multiple populations; toxicologists looking for alternatives to animal models for toxicity testing; and anyone interested in finding out more about our products and services.
A professor with dual appointments in Mechanical Engineering and Biomedical Engineering at The University of Texas at Austin, Dr Ben-Yakar’s research focuses on the creation of imaging technologies and novel laser surgery with high precision. Educated at Stanford and the Technion in Israel, with post-doctoral study at Harvard, and using her NIH Director’s Transformative Research Award, Dr Ben-Yakar began the research that has culminated in the launch of Newormics, LLC
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Evan Hegarty, co-founder, received his M.S. in Mechanical Engineering at The University of Texas at Austin while developing the technology and IP that lead to the launch of Newormics, LLC. As the Director of Manufacturing and Product development, and Principal Investigator of NIH SBIR grants at Newormics, Evan is responsible for development of all chip and system designs, creating production schedules, optimizing production methods, managing team members, identifying customer needs, developing future products, and reinforcing GLP and GMP.
Dr. Yunki Im is a molecular geneticist with expertise in autophagy, mitophagy, unfolded protein response, post-translational modifications (sumoylation and ubiquitination), and mitochondrial biology applied to study neurodegenerative disease and cardiac vascular disease in C. elegans and mice. He was educated at GIST in Korea, with post-doctoral study at University of Rochester, NY.
Jacob Moore completed his master’s and PhD in mechanical engineering at the University of Texas at Austin before joining the Newormics team. From his experimental research in the gas turbine industry, he developed a hands-on expertise in thermal/fluids systems that he is applying to chip and system designs. In addition, he is using his automated laboratory measurement experience to mature automation designs using Newormics technology.
Dr. Adam Laing is a molecular and cellular biologist educated at the University of Edinburgh, and leads the Research and Development activities of Newormics. He is responsible for testing and characterizing the new devices and imaging methods, and development of toxicology and drug screening assays in C. elegans as well as tissue organoids.
Dr. Lento is a serial COO/VPO executive for life science startups with broad skills in pharmaceuticals, medical devices, and diagnostics. With a unique background of equal parts government, public and private sector service, Dr. Lento holds a PhD in Biochemistry and additional credentials in Drug Evaluation, Pharmaceutical Sciences, and Corporate Governance.