vivoChip™-96x is the first large-scale imaging and screening platform for C. elegans. The vivoChip™-96x enables rapid high-content screening of ~4,000 animals immobilized in their lateral orientation.
- Immobilize up to 3,840 C. elegans in 3 minutes
- Orientation efficiency >90%
- vivoChip™-96x for L4–YA stage animals
- Thin glass substrate for high-resolution imaging
A high-throughput screening of polyglutamine aggregation model in C. elegans was tested with ~1,000 FDA approved library to identify four hits and one with strong dose response.
Ref: Mondal et al. Nat. Commun. 2016 DOI:10.1038/ncomms13023