See how vivoChip® enables rapid immobilization and alignment of multiple worms for high resolution imaging
vivoChip®-96x is the first large-scale imaging and screening platform for C. elegans. The vivoChip-96x enables rapid high-content screening of ~4,000 animals immobilized in their lateral orientation.
Loading C. elegans to image PolyQ protein aggregation
C. elegans with a YFP reporter showing PolyQ protein aggregation (a worm model for Huntington’s disease) are loaded into a vivoChip for immobilization and high-resolution imaging. Immobilized worms are then imaged so the aggregates can be quantified in each animal.